Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Summary: Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may occur in response to LIF-STAT3 signaling; however, l...

Full description

Bibliographic Details
Main Authors:	Hideyuki Murayama, Hideki Masaki, Hideyuki Sato, Tomonari Hayama, Tomoyuki Yamaguchi, Hiromitsu Nakauchi
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Series:	Stem Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671114003609

Similar Items

Epiblast ground state is controlled by canonical Wnt/β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells.
by: Tomoyuki Sumi, et al.
Published: (2013-01-01)

A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.
by: Masahide Seki, et al.
Published: (2014-01-01)

Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.
by: Tomoyuki Yamaguchi, et al.
Published: (2012-01-01)

Epigenetic reprogramming of epiblast stem cells to a naïve pluripotent state
by: Gillich, Astrid
Published: (2012)

Aberrant nuclear localization of β-catenin without genetic alterations in β-catenin or Axin genes in esophageal cancer
by: Shinoda Noriyuki, et al.
Published: (2007-02-01)

Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation
by: Sanae Hamanaka, et al.
Published: (2018-10-01)

Transient Expression of WNT2 Promotes Somatic Cell Reprogramming by Inducing β-Catenin Nuclear Accumulation
by: Mizuki Kimura, et al.
Published: (2016-06-01)

Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors
by: Yann Tapponnier, et al.
Published: (2017-10-01)

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells.
by: Le Tran Phuc Khoa, et al.
Published: (2016-01-01)

Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
by: Teppei Goto, et al.
Published: (2019-02-01)

Direct reprogramming of somatic cells into human induced naive pluripotent stem cells, a novel model of preimplantation epiblast cells
by: Kilens, Stéphanie
Published: (2017)

Wnt/β-Catenin Signaling Triggers Neuron Reprogramming and Regeneration in the Mouse Retina
by: Daniela Sanges, et al.
Published: (2013-07-01)

ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast
by: Yang Yu, et al.
Published: (2018-01-01)

High‐throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming
by: Qian Gao, et al.
Published: (2021-05-01)

Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector
by: Naoaki Mizuno, et al.
Published: (2018-11-01)

Induction of Primordial Germ Cells from Pluripotent Epiblast
by: Ying Ying, et al.
Published: (2002-01-01)

β-Catenin Fluctuates in Mouse ESCs and Is Essential for Nanog-Mediated Reprogramming of Somatic Cells to Pluripotency
by: Lucia Marucci, et al.
Published: (2014-09-01)

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
by: Kai Kretzschmar, et al.
Published: (2016-01-01)

Generation of Mouse Parthenogenetic Epiblast Stem Cells and Their Imprinting Patterns
by: Bong Jong Seo, et al.
Published: (2019-10-01)

Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success.
by: Sebastian Thomas Balbach, et al.
Published: (2012-01-01)

Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success
by: Balbach, Sebastian Thomas, et al.
Published: (2012)

Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt.
by: Frank A Suprynowicz, et al.
Published: (2017-01-01)

The Role of Wnt/β-catenin Signaling Pathway in Rat Primordial Germ Cells Reprogramming and Induction into Pluripotent State
by: Alireza Mohammadi, et al.
Published: (2014-06-01)

Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling
by: Sokol Sergei Y, et al.
Published: (2005-02-01)

Factors regulating the nuclear localization of β-catenin in acute myeloid leukaemia
by: Ridsdale, Jenna
Published: (2018)

AMPK activation reverts mouse epiblast stem cells to naive state
by: Yajing Liu, et al.
Published: (2021-07-01)

An in vitro stem cell model of human epiblast and yolk sac interaction
by: Kirsty ML Mackinlay, et al.
Published: (2021-08-01)

Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett’s Esophagus: Regulation via Dickkopf-1
by: Orestis Lyros, et al.
Published: (2015-07-01)

Anti-apoptotic Regulation Contributes to the Successful Nuclear Reprogramming Using Cryopreserved Oocytes
by: Ah Reum Lee, et al.
Published: (2019-03-01)

Comparison of in vitro Neuronal Differentiation Capacity Between Mouse Epiblast Stem Cells Derived From Nuclear Transfer and Naturally Fertilized Embryos
by: Tong Li, et al.
Published: (2018-10-01)

Nuclear Regulation of Wnt/β-Catenin Signaling: It’s a Complex Situation
by: Christin C. Anthony, et al.
Published: (2020-08-01)

Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin.
by: Terence J Van Raay, et al.
Published: (2011-04-01)

STAT3 activation is involved in nuclear accumulation of β-catenin in colorectal cancer
by: Kawada, Mayumi
Published: (2011)

Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State
by: A. S. Devika, et al.
Published: (2021-01-01)

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
by: Shohag Bhargava, et al.
Published: (2017-08-01)

E-cadherin promotes incorporation of mouse epiblast stem cells into normal development.
by: Satoshi Ohtsuka, et al.
Published: (2012-01-01)

In Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation
by: Yali Huang, et al.
Published: (2012-12-01)

Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells
by: Chang Liu, et al.
Published: (2018-07-01)

Cell behaviour during epithelial wound closure in the chick extra-embryonic epiblast
by: Goodwin, Mark A. J.
Published: (1986)

Paying the Toll in Nuclear Reprogramming
by: Chun Liu, et al.
Published: (2017-08-01)