Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burden.

Leishmania donovani is an intracellular protozoan parasite that causes visceral leishmaniasis (VL). Antimonials (SSG) have long been the first-line treatment against VL, but have now been replaced by miltefosine (MIL) in the Indian subcontinent due to the emergence of SSG-resistance. Our previous st...

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Bibliographic Details
Main Authors: Manu Vanaerschot, Simonne De Doncker, Suman Rijal, Louis Maes, Jean-Claude Dujardin, Saskia Decuypere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3148249?pdf=render