Novel peptide sequence ("IQ-tag") with high affinity for NIR fluorochromes allows protein and cell specific labeling for in vivo imaging.

Novel peptide sequence ("IQ-tag") with high affinity for NIR fluorochromes allows protein and cell specific labeling for in vivo imaging.

Probes that allow site-specific protein labeling have become critical tools for visualizing biological processes.Here we used phage display to identify a novel peptide sequence with nanomolar affinity for near infrared (NIR) (benz)indolium fluorochromes. The developed peptide sequence ("IQ-tag&...

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Bibliographic Details
Main Authors: Kimberly A Kelly, Jonathan Carson, Jason R McCarthy, Ralph Weissleder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1919420?pdf=render

Internet

http://europepmc.org/articles/PMC1919420?pdf=render

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