Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes

<p>Abstract</p> <p>Background</p> <p>In recent years, several lines of evidence have shown an increase in Parkinson's disease prevalence in rural environments where pesticides are heavily used. Although, the underlying mechanism for neuronal degeneration in sporadi...

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Bibliographic Details
Main Authors: BK Binukumar, Bal Amanjit, Kandimalla Ramesh JL, Gill Kiran
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/3/1/35