Higher proportion of inactive Gsk3β in platelets of elderly patients with bipolar disorder: an effect of treatment?

Objective: It has been postulated that mood stabilizers inhibit glycogen synthase kinase 3-beta (Gsk3β) activity, mainly through its phosphorylation on serine-9 (Ser9). However, in vivo studies addressing Gsk3β activity in patients with bipolar disorder are scarce. Here, we compare Gsk3β inactivatio...

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Bibliographic Details
Main Authors: Rodolfo Braga Ladeira, Helena Passarelli Giroud Joaquim, Leda Leme Talib, Paula Villela Nunes, Orestes Vicente Forlenza
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2013-09-01
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462013000300274&lng=en&tlng=en