Protocols and pitfalls in obtaining fatty acid-binding proteins for biophysical studies of ligand-protein and protein-protein interactions

Protocols and pitfalls in obtaining fatty acid-binding proteins for biophysical studies of ligand-protein and protein-protein interactions

Adipocyte fatty acid-binding protein (AFABP: FABP4) is a member of the intracellular lipid-binding protein family that is thought to target long-chain fatty acids to nuclear receptors such as peroxisome proliferator-activated receptor gamma (PPARγ), which in turn plays roles in insulin resistance an...

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Bibliographic Details
Main Authors: Qian Wang, Samar Rizk, Cédric Bernard, May Poh Lai, David Kam, Judith Storch, Ruth E. Stark
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Protein
Ligand
Fatty acid-binding protein
Homodimer
Disulfide bond
Delipidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817300651

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http://www.sciencedirect.com/science/article/pii/S2405580817300651

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