Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice

Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice

Diet is a major factor determining gut microbiota composition and perturbances in this complex ecosystem are associated with the inflammatory bowel disease (IBD). Here, we used gnotobiotic approach to analyze, how interaction between diet rich in proteins and gut microbiota influences the sensitivit...

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Bibliographic Details
Main Authors: Klara Kostovcikova, Stepan Coufal, Natalie Galanova, Alena Fajstova, Tomas Hudcovic, Martin Kostovcik, Petra Prochazkova, Zuzana Jiraskova Zakostelska, Martina Cermakova, Blanka Sediva, Marek Kuzma, Helena Tlaskalova-Hogenova, Miloslav Kverka
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
dietary protein
microbiota
colitis
germ-free
macrophage
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00919/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00919/full

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