Histone Deacetylase 6 Knockout Mice Exhibit Higher Susceptibility to Influenza A Virus Infection

The host innate defence against influenza virus infection is an intricate system with a plethora of antiviral factors involved. We have identified host histone deacetylase 6 (HDAC6) as an anti-influenza virus factor in cultured cells. Consistent with this, we report herein that HDAC6 knockout (KO) m...

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Bibliographic Details
Main Authors: Mark Zanin, Jennifer DeBeauchamp, Gowthami Vangala, Richard J. Webby, Matloob Husain
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
IAV
Online Access:https://www.mdpi.com/1999-4915/12/7/728