P-Cresylsulfate, the Protein-Bound Uremic Toxin, Increased Endothelial Permeability Partly Mediated by Src-Induced Phosphorylation of VE-Cadherin

The goal of our study was to investigate the impact of p-cresylsulfate (PCS) on the barrier integrity in human umbilical vein endothelial cell (HUVEC) monolayers and the renal artery of chronic kidney disease (CKD) patients. We measured changes in the transendothelial electrical resistance (TEER) of...

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Bibliographic Details
Main Authors: Shih-Chieh Chen, Shin-Yin Huang, Chia-Chun Wu, Chiung-Fang Hsu
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/2/62