A proximity-based graph clustering method for the identification and application of transcription factor clusters

Abstract Background Transcription factors (TFs) form a complex regulatory network within the cell that is crucial to cell functioning and human health. While methods to establish where a TF binds to DNA are well established, these methods provide no information describing how TFs interact with one a...

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Bibliographic Details
Main Authors: Maxwell Spadafore, Kayvan Najarian, Alan P. Boyle
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1935-y