Human Bone Marrow Mesenchymal Stem Cells Regulate Biased DNA Segregation in Response to Cell Adhesion Asymmetry

Biased DNA segregation is a mitotic event in which the chromatids carrying the original template DNA strands and those carrying the template copies are not segregated randomly into the two daughter cells. Biased segregation has been observed in several cell types, but not in human mesenchymal stem...

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Bibliographic Details
Main Authors: Delphine Freida, Severine Lecourt, Audrey Cras, Valérie Vanneaux, Gaelle Letort, Xavier Gidrol, Laurent Guyon, Jerome Larghero, Manuel Thery
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005421