Impact of Minimal Residual Disease Detection by Next-Generation Flow Cytometry in Multiple Myeloma Patients with Sustained Complete Remission after Frontline Therapy

Impact of Minimal Residual Disease Detection by Next-Generation Flow Cytometry in Multiple Myeloma Patients with Sustained Complete Remission after Frontline Therapy

Abstract. Minimal residual disease (MRD) was monitored in 52 patients with sustained CR (≥2 years) after frontline therapy using next-generation flow (NGF) cytometry. 25% of patients initially MRD- reversed to MRD+. 56% of patients in sustained CR were MRD+; 45% at the level of 10−5; 17% at 10−6. Al...

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Main Authors: Evangelos Terpos, Ioannis V. Kostopoulos, Efstathios Kastritis, Ioannis Ntanasis-Stathopoulos, Magdalini Migkou, Pantelis Rousakis, Alexandra T. Argyriou, Nikolaos Kanellias, Despina Fotiou, Evangelos Eleutherakis-Papaiakovou, Maria Gavriatopoulou, Dimitrios C. Ziogas, Aristea-Maria Papanota, Marilyn Spyropoulou-Vlachou, Ioannis P. Trougakos, Ourania E. Tsitsilonis, Bruno Paiva, Meletios A. Dimopoulos
Format: Article
Language:English
Published: Wolters Kluwer 2019-12-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000300

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http://journals.lww.com/10.1097/HS9.0000000000000300

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