The Influence of a KDT501, a Novel Isohumulone, on Adipocyte Function in Humans

The Influence of a KDT501, a Novel Isohumulone, on Adipocyte Function in Humans

ObjectiveIn a phase II clinical trial in nine obese, insulin-resistant humans, we observed that treatment with KDT501, a novel isohumulone drug, increased total and high-molecular weight (HMW) adiponectin in plasma. The objective was to determine whether KDT501 increased adiponectin secretion from s...

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Bibliographic Details
Main Authors: Brian S. Finlin, Beibei Zhu, Bernard P. Kok, Cristina Godio, Philip M. Westgate, Neile Grayson, Robert Sims, Jeffrey S. Bland, Enrique Saez, Philip A. Kern
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Endocrinology
Subjects:
adiponectin
adipocyte secretion
adipose tissue biology
gene expression profiling
metabolic syndrome
mitochondria
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00255/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2017.00255/full

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