Assessment of Behavioral Characteristics With Procedures of Minimal Human Interference in the mdx Mouse Model for Duchenne Muscular Dystrophy

Assessment of Behavioral Characteristics With Procedures of Minimal Human Interference in the mdx Mouse Model for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a severe, progressive neuromuscular disorder caused by mutations in the DMD gene resulting in loss of functional dystrophin protein. The muscle dystrophin isoform is essential to protect muscles from contraction-induced damage. However, most dystrophin isoforms a...

Full description

Bibliographic Details
Main Authors: Sarah Engelbeen, Annemieke Aartsma-Rus, Bastijn Koopmans, Maarten Loos, Maaike van Putten
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
cognitive abnormalities
dystrophin (DMD)
behavior
cognitive flexibility
spatial working memory
anxiety
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2020.629043/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2020.629043/full

Similar Items