Co-option of the piRNA Pathway for Germline-Specific Alternative Splicing of C. elegans TOR

Many eukaryotic genes contain embedded antisense transcripts and repetitive sequences of unknown function. We report that male germline-specific expression of an antisense transcript contained in an intron of C. elegans Target of Rapamycin (TOR, let-363) is associated with (1) accumulation of endo-s...

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Bibliographic Details
Main Authors: Sergio Barberán-Soler, Laura Fontrodona, Anna Ribó, Ayelet T. Lamm, Camilla Iannone, Julián Cerón, Ben Lehner, Juan Valcárcel
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714006792