Use of haplotypes to identify regions harbouring lethal recessive variants in pigs

Abstract Background Lethal recessive genetic variants are maintained at relatively low frequencies in a population in the heterozygous state, but by definition are fatal and therefore unobserved in the homozygous state. Since haplotypes allow the tagging of rare and untyped genetic variants, they ha...

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Bibliographic Details
Main Authors: David M. Howard, Ricardo Pong-Wong, Pieter W. Knap, John A. Woolliams
Format: Article
Language:deu
Published: BMC 2017-07-01
Series:Genetics Selection Evolution
Online Access:http://link.springer.com/article/10.1186/s12711-017-0332-3