Polyamine Oxidase Is Involved in Spermidine Reduction of Transglutaminase Type 2-Catalyzed <i>β</i>H-Crystallins Polymerization in Calcium-Induced Experimental Cataract
In an in vitro Ca<sup>2+</sup>-induced cataract model, the progression of opacification is paralleled by a rapid decrease of the endogenous levels of spermidine (SPD) and an increase of transglutaminase type 2 (TG2, EC 2.3.2.13)-catalyzed lens crystallins cross-linking by protein-bound &...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/15/5427 |