Alzheimer's and Seizures: Interleukin-18, Indoleamine 2,3-Dioxygenase and Quinolinic Acid
Emergent seizures are common in Alzheimer's disease (AD), although the mechanisms mediating this are unknown. It is proposed that stress induced interleukin-18 (IL-18), via interferon-gamma (IFNy) and independently, increases indoleamine 2,3-dioxygenase (IDO) and subsequent quinolinic acid (QA)...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-01-01
|
| Series: | International Journal of Tryptophan Research |
| Online Access: | https://doi.org/10.4137/IJTR.S4603 |