Solution-phase vs surface-phase aptamer-protein affinity from a label-free kinetic biosensor.

Aptamers are selected DNA ligands that target biomolecules such as proteins. In recent years, they are showing an increasing interest as potential therapeutic agents or recognition elements in biosensor applications. In both cases, the need for characterizing the mating between the target and the ap...

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Bibliographic Details
Main Authors: Camille Daniel, Yoann Roupioz, Didier Gasparutto, Thierry Livache, Arnaud Buhot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24069412/pdf/?tool=EBI