Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates

Rhee, Pokrovskaya et al. utilize 3D electron microscopy of mouse jugular vein puncture wounds to reveal thrombi structured around localized, nucleated platelet aggregates that produced a vaulted thrombus capped by extravascular platelet adherence. As a result, the authors propose a “Cap and Build” p...

Full description

Bibliographic Details
Main Authors: Sung W. Rhee, Irina D. Pokrovskaya, Kelly K. Ball, Kenny Ling, Yajnesh Vedanaparti, Joshua Cohen, Denzel R. D. Cruz, Oliver S. Zhao, Maria A. Aronova, Guofeng Zhang, Jeffrey A. Kamykowski, Richard D. Leapman, Brian Storrie
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02615-y