Digenic Inheritance in Cystinuria Mouse Model.

Cystinuria is an aminoaciduria caused by mutations in the genes that encode the two subunits of the amino acid transport system b0,+, responsible for the renal reabsorption of cystine and dibasic amino acids. The clinical symptoms of cystinuria relate to nephrolithiasis, due to the precipitation of...

Full description

Bibliographic Details
Main Authors: Meritxell Espino, Mariona Font-Llitjós, Clara Vilches, Eduardo Salido, Esther Prat, Miguel López de Heredia, Manuel Palacín, Virginia Nunes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4567282?pdf=render