Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model

<p>Abstract</p> <p>Background</p> <p>We have previously shown that small molecule PDGF receptor tyrosine kinase inhibitors (RTKI) can drastically attenuate radiation-induced pulmonary fibrosis if the drug administration starts at the time of radiation during acute infla...

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Bibliographic Details
Main Authors: Gröne Hermann-Josef, Abdollahi Amir, Li Minglun, Lipson Kenneth E, Belka Claus, Huber Peter E
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/4/1/66