Effect of a new inhibitor of cholesterol biosynthesis (AY 9944) on serum and tissue sterols in the rat
AY 9944 is a novel inhibitor of cholesterol biosynthesis which appears to act on the Δ7-reductase enzyme, interfering with the conversion of 7-dehydrocholesterol to cholesterol. In all tissues studied, with the exception of the lens, there was a reduction in cholesterol and a marked accumulation of...
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| Format: | Article |
| Language: | English |
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Elsevier
1966-01-01
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| Series: | Journal of Lipid Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520395936 |