Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers

Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers

Global-genome nucleotide excision repair (GG-NER) prevents genome instability by excising a wide range of structurally unrelated DNA base adducts and crosslinks induced by chemical carcinogens, ultraviolet (UV) radiation or intracellular metabolic by-products. As a versatile damage sensor, xeroderma...

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Bibliographic Details
Main Authors: Peter eRuethemann, Chiara eBalbo Pogliano, Hanspeter eNaegeli
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Genetics
Subjects:
Aging
DNA Repair
Sunlight
Cancer
SUMO
UV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00068/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00068/full

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