The Protective Effect of Magnolol in Osteoarthritis: In vitro and in vivo Studies

The Protective Effect of Magnolol in Osteoarthritis: In vitro and in vivo Studies

Osteoarthritis (OA), defined as a long-term progressive joint disease, is characterized by cartilage impairment and erosion. In recent decades, magnolol, as a type of lignin extracted from Magnolia officinalis, has been proved to play a potent anti-inflammatory role in various diseases. The current...

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Bibliographic Details
Main Authors: Zhi-Chao Hu, Zu-Cheng Luo, Bing-Jie Jiang, Xin Fu, Jiang-Wei Xuan, Xiao-Bin Li, Yu-Jie Bian, Wen-Fei Ni, Ji-Xin Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
magnolol
PI3K/Akt/NF-κB
osteoarthritis
interleukin-1 beta
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00393/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00393/full

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