ALA-PpIX mediated photodynamic therapy of malignant gliomas augmented by hypothermia.

Malignant gliomas are highly invasive, difficult to treat, and account for 2% of cancer deaths worldwide. Glioblastoma Multiforme (GBM) comprises the most common and aggressive intracranial tumor. The study hypothesis is to investigate the modification of Photodynamic Therapy (PDT) efficacy by mild...

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Bibliographic Details
Main Authors: Carl J Fisher, Carolyn Niu, Warren Foltz, Yonghong Chen, Elena Sidorova-Darmos, James H Eubanks, Lothar Lilge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5536352?pdf=render