Origins of intestinal ABCA1-mediated HDL-cholesterol*

Origins of intestinal ABCA1-mediated HDL-cholesterol*

The origins of cholesterol utilized by intestinal ABCA1 were investigated in the human intestinal cell line Caco-2. Influx of apical membrane cholesterol increases ABCA1 mRNA and mass, resulting in enhanced efflux of HDL-cholesterol. Luminal (micellar) cholesterol and newly synthesized cholesterol a...

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Bibliographic Details
Main Authors: F. Jeffrey Field, Kim Watt, Satya N. Mathur
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Journal of Lipid Research
Subjects:
cholesterol trafficking
Caco-2 cells
cholesterol
lipoproteins
high density lipoproteins
ABCA1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345910

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http://www.sciencedirect.com/science/article/pii/S0022227520345910

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