Screening for cyclooxygenase 2 inhibitors from natural compounds of Radix Glycyrrhizae using computer simulation

Screening for cyclooxygenase 2 inhibitors from natural compounds of Radix Glycyrrhizae using computer simulation

Objective: To explore the molecular basis of the effects of Gancao (Radix Glycyrrhizae, GC) on inflammation through the inhibition of cyclooxygenase 2 (COX-2). Methods: The Discovery Studio 4.5 System was used to predict the physicochemical properties of GC molecular compounds. The Ligand Profiler w...

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Bibliographic Details
Main Authors: Ming Yang, Yi Jin, Li-Ping Yang
Format: Article
Language:English
Published: Hong Kong Gold Orchid Science and Technology Co., Limited 2018-05-01
Series:Traditional Medicine Research
Subjects:
Radix Glycyrrhizae COX-2 Pharmacophores Molecular docking Physicochemical properties
Radix Glycyrrhizae
COX-2
Pharmacophores
Molecular docking
Physicochemical properties
Online Access:http://www.tmrjournal.com/EN/abstract/abstract246.shtml

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http://www.tmrjournal.com/EN/abstract/abstract246.shtml

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