Microwell scaffolds for the extrahepatic transplantation of islets of Langerhans.

Allogeneic islet transplantation into the liver has the potential to restore normoglycemia in patients with type 1 diabetes. However, the suboptimal microenvironment for islets in the liver is likely to be involved in the progressive islet dysfunction that is often observed post-transplantation. Thi...

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Bibliographic Details
Main Authors: Mijke Buitinga, Roman Truckenmüller, Marten A Engelse, Lorenzo Moroni, Hetty W M Ten Hoopen, Clemens A van Blitterswijk, Eelco Jp de Koning, Aart A van Apeldoorn, Marcel Karperien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667808?pdf=render