Mineralocorticoid Receptor Antagonists Eplerenone and Spironolactone Modify Adrenal Cortex Morphology and Physiology

Mineralocorticoid Receptor Antagonists Eplerenone and Spironolactone Modify Adrenal Cortex Morphology and Physiology

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs spironolactone and eplerenone influence adrenal cortical physiology and morphology. Spontaneous hypertensive rats (SHR,...

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Bibliographic Details
Main Authors: Sofia S. Pereira, Liliana Carvalho, Madalena M. Costa, Armindo Melo, Isabel M. P. L. V. O. Ferreira, Celso E. Gomez-Sanchez, Mariana P. Monteiro, Gavin Vinson, Duarte Pignatelli
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
adrenal cortex
mineralocorticoid receptor antagonists
eplerenone
spironolactone
steroids
Online Access:https://www.mdpi.com/2227-9059/9/4/441

Internet

https://www.mdpi.com/2227-9059/9/4/441

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