A systematic comparison of the anti-tumoural activity and toxicity of the three Adv-TKs.

Adenovirus 5 vectors, known respectively as, the first generation, second generation and oncolytic adenovirus, have been studied extensively in preclinical and clinical trials. However, hitherto few systemic evaluations of the efficacy and toxicity of these adenoviral vectors that have reflected the...

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Main Authors: Qinglei Gao, Caihong Chen, Teng Ji, Peng Wu, Zhiqiang Han, Haiyan Fang, Fei Li, Yi Liu, Wencheng Hu, Danni Gong, Zeyu Zhang, Shixuan Wang, Jianfeng Zhou, Ding Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983249?pdf=render