Ectopic Lymphoid Follicles in Multiple Sclerosis: Centers for Disease Control?

While the contribution of autoreactive CD4+ T cells to the pathogenesis of Multiple Sclerosis (MS) is widely accepted, the advent of B cell-depleting monoclonal antibody (mAb) therapies has shed new light on the complex cellular mechanisms underlying MS pathogenesis. Evidence supports the involvemen...

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Bibliographic Details
Main Authors: Austin Negron, Olaf Stüve, Thomas G. Forsthuber
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Neurology
Subjects:
GCR
ELF
TFH
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.607766/full