Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.

Hepatosplenic T-cell lymphoma (HSTL) is an aggressive lymphoma cytogenetically characterized by isochromosome 7q [i(7)(q10)], of which the molecular consequences remain unknown. We report here results of an integrative genomic and transcriptomic (expression microarray and RNA-sequencing) study of si...

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Main Authors: Julio Finalet Ferreiro, Leila Rouhigharabaei, Helena Urbankova, Jo-Anne van der Krogt, Lucienne Michaux, Shashirekha Shetty, Laszlo Krenacs, Thomas Tousseyn, Pascale De Paepe, Anne Uyttebroeck, Gregor Verhoef, Tom Taghon, Peter Vandenberghe, Jan Cools, Iwona Wlodarska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25057852/pdf/?tool=EBI