Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila

Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila

Abstract Background Thermophilic filamentous fungus Myceliophthora thermophila has great capacity for biomass degradation and is an attractive system for direct production of enzymes and chemicals from plant biomass. Its industrial importance inspired us to develop genome editing tools to speed up t...

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Bibliographic Details
Main Authors: Qian Liu, Yongli Zhang, Fangya Li, Jingen Li, Wenliang Sun, Chaoguang Tian
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Biotechnology for Biofuels
Subjects:
CRISPR–Cas12a
CRISPR–Cas9
Genome editing
Myceliophthora thermophila
Marker recycling
Cellulase
Online Access:https://doi.org/10.1186/s13068-019-1637-y

Internet

https://doi.org/10.1186/s13068-019-1637-y

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