Key role for store-operated Ca2+ channels in activating gene expression in human airway bronchial epithelial cells.

Ca2+ entry into airway epithelia is important for activation of the NFAT family of transcription factors and expression of genes including epidermal growth factor that help orchestrate local inflammatory responses. However, the identity of epithelial Ca2+ channel that activates these transcriptional...

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Bibliographic Details
Main Authors: Krishna Samanta, Daniel Bakowski, Anant B Parekh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4144895?pdf=render