Malignant B cells induce the conversion of CD4+CD25- T cells to regulatory T cells in B-cell non-Hodgkin lymphoma.

Malignant B cells induce the conversion of CD4+CD25- T cells to regulatory T cells in B-cell non-Hodgkin lymphoma.

Recent evidence has demonstrated that regulatory T cells (Treg) were enriched in the tumor sites of patients with B-cell non-Hodgkin lymphoma (NHL). However, the causes of enrichment and suppressive mechanisms need to be further elucidated. Here we demonstrated that CD4(+)CD25(+)FoxP3(+)CD127(lo) Tr...

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Bibliographic Details
Main Authors: Yixiang Han, Jianbo Wu, Laixi Bi, Shudao Xiong, Shenmeng Gao, Lihui Yin, Lei Jiang, Chiqi Chen, Kang Yu, Shenghui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3235139?pdf=render

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http://europepmc.org/articles/PMC3235139?pdf=render

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