Effect of correlated tRNA abundances on translation errors and evolution of codon usage bias.

Despite the fact that tRNA abundances are thought to play a major role in determining translation error rates, their distribution across the genetic code and the resulting implications have received little attention. In general, studies of codon usage bias (CUB) assume that codons with higher tRNA a...

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Bibliographic Details
Main Authors: Premal Shah, Michael A Gilchrist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2940732?pdf=render