Deactivation of the JNK Pathway by GSTP1 Is Essential to Maintain Sperm Functionality

Fifty percent of male subfertility diagnosis is idiopathic and is usually associated with genetic abnormalities or protein dysfunction, which are not detectable through the conventional spermiogram. Glutathione S-transferases (GSTs) are antioxidant enzymes essential for preserving sperm function and...

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Bibliographic Details
Main Authors: Marc Llavanera, Yentel Mateo-Otero, Ariadna Delgado-Bermúdez, Sandra Recuero, Samuel Olives, Isabel Barranco, Marc Yeste
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.627140/full