Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis

Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis

Abstract Background This study compared the effects of pre-transplantation minimal residual disease (pre-MRD) on outcomes in AML patients who underwent human leukocyte antigen-matched sibling donor transplantation (MSDT) or who received unmanipulated haploidentical allografts. Methods A retrospectiv...

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Bibliographic Details
Main Authors: Ying-Jun Chang, Yu Wang, Yan-Rong Liu, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei Han, Yu-Qian Sun, Chen-Hua Yan, Fei-Fei Tang, Xiao-Dong Mo, Kai-Yan Liu, Xiao-Jun Huang
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Hematology & Oncology
Subjects:
Acute myeloid leukemia
Allogeneic stem cell transplantation
Minimal residual disease
Multiparameter flow cytometry
Unmanipulated haploidentical allografts
Online Access:http://link.springer.com/article/10.1186/s13045-017-0502-3

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http://link.springer.com/article/10.1186/s13045-017-0502-3

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