Studying polymorphic variants of the NAT2 gene (NAT2*5 and NAT2*7) in Nenets populations of Northern Siberia

Studying polymorphic variants of the NAT2 gene (NAT2*5 and NAT2*7) in Nenets populations of Northern Siberia

Abstract Background N-acetyltransferase 2 plays a crucial role in the metabolism of a wide range of xenobiotics, including many drugs, carcinogens, and other chemicals in the human environment. The article presents for the first time data on the frequency of two important “slow” variants of NAT2 gen...

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Bibliographic Details
Main Authors: Roza Pavlovna Tiis, Ludmila Pavlovna Osipova, Daria Veniaminovna Lichman, Elena Nikolaevna Voronina, Maxim Leonidovich Filipenko
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Genetics
Subjects:
Xenobiotics
NAT2 gene
NAT2*5, rs1801280
NAT2*7, rs1799931
Forest and Tundra Nenets
Northern Siberia
Online Access:http://link.springer.com/article/10.1186/s12863-020-00909-4

Internet

http://link.springer.com/article/10.1186/s12863-020-00909-4

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