Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy

Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy

Abstract Background Umbilical cord mesenchymal stem cell (HUCMSC)-based therapies were previously utilised for cartilage regeneration because of the chondrogenic potential of MSCs. However, chondrogenic differentiation of HUCMSCs is limited by the administration of growth factors like TGF-β that may...

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Bibliographic Details
Main Authors: Ke Ma, Bo Zhu, Zetao Wang, Peian Cai, Mingwei He, Danyan Ye, Guohua Yan, Li Zheng, Lujun Yang, Jinmin Zhao
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Nanobiotechnology
Subjects:
Autophagy
Chondrocytes
Chondrogenesis
Extracellular vesicles
Human umbilical cord mesenchymal stem cells
Online Access:http://link.springer.com/article/10.1186/s12951-020-00708-0

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http://link.springer.com/article/10.1186/s12951-020-00708-0

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