Histological Characterization of the Tumorigenic "Peri-Necrotic Niche" Harboring Quiescent Stem-Like Tumor Cells in Glioblastoma.

BACKGROUND:Characterization of the niches for stem-like tumor cells is important to understand and control the behavior of glioblastomas. Cell-cycle quiescence might be a common mechanism underlying the long-term maintenance of stem-cell function in normal and neoplastic stem cells, and our previous...

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Bibliographic Details
Main Authors: Aya Ishii, Tokuhiro Kimura, Hirokazu Sadahiro, Hiroo Kawano, Keiyo Takubo, Michiyasu Suzuki, Eiji Ikeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4723051?pdf=render