Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet

Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet

Calorie restriction (CR) is considered one of the most robust ways to extend life span and reduce the risk of age-related diseases, including cancer, as shown in many different organisms, whereas opposite effects have been associated with high fat diets (HFDs). Despite the proven contribution of sir...

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Bibliographic Details
Main Authors: Mohamed A. Ahmed, Carol O'Callaghan, Elliot D. Chang, Haiyan Jiang, Athanassios Vassilopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
SIRT2
SIRT3
calorie restriction
high fat diet
cancer
aging
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01462/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01462/full

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