Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators

Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators

This study was aimed to evaluate the possible protective effects of ursolic acid (UA) against gamma radiation induced damage both in vitro as well as in vivo. It was observed that the exposure to gamma radiation dose- and time-dependently caused a significant decrease in the cell viability, while th...

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Bibliographic Details
Main Authors: Hong Wang, Meng-Kwoon Sim, Weng Keong Loke, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Feng Ru Tang, Gautam Sethi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
radiation
ursolic acid
NF-κB
TNF-α
NO
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00352/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00352/full

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