Immunotherapy reduces allergen-mediated CD66b expression and myeloperoxidase levels on human neutrophils from allergic patients.

CD66b is a member of the carcinoembryonic antigen family, which mediates the adhesion between neutrophils and to endothelial cells. Allergen-specific immunotherapy is widely used to treat allergic diseases, and the molecular mechanisms underlying this therapy are poorly understood. The present work...

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Bibliographic Details
Main Authors: Rocio Aroca, Cristina Chamorro, Antonio Vega, Inmaculada Ventura, Elisa Gómez, Ramón Pérez-Cano, Miguel Blanca, Javier Monteseirín
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3989194?pdf=render