Antibodies towards Tyrosine Amyloid-Like Fibrils Allow Toxicity Modulation and Cellular Imaging of the Assemblies

The amino acid tyrosine forms cytotoxic amyloid-like fibrils by molecular self-assembly. However, the production of antibodies towards tyrosine assemblies, reflecting their presentation to the immune system, was not demonstrated yet. Here, we describe the production of antibodies that specifically r...

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Bibliographic Details
Main Authors: Dor Zaguri, Topaz Kreiser, Shira Shaham-Niv, Ehud Gazit
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/6/1273