Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis

Abstract Background Metabolic syndrome (MetS) may be associated with knee osteoarthritis (OA), but the association between the individual components and OA are not well-understood. We aimed to study the effect of hypercholesterolemia on synovial inflammation in knee OA. Methods OA was surgically ind...

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Bibliographic Details
Main Authors: Ane Larrañaga-Vera, Ana Lamuedra, Sandra Pérez-Baos, Ivan Prieto-Potin, Leticia Peña, Gabriel Herrero-Beaumont, Raquel Largo
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Hypercholesterolemia
Synovial inflammation
Metabolic syndrome
Macrophages
Synovial adipose tissue
Online Access:http://link.springer.com/article/10.1186/s13075-017-1473-z

Internet

http://link.springer.com/article/10.1186/s13075-017-1473-z

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