Evaluation of the Predictive Ability, Environmental Regulation and Pharmacogenetics Utility of a BMI-Predisposing Genetic Risk Score during Childhood and Puberty

Evaluation of the Predictive Ability, Environmental Regulation and Pharmacogenetics Utility of a BMI-Predisposing Genetic Risk Score during Childhood and Puberty

Polygenetic risk scores (pGRSs) consisting of adult body mass index (BMI) genetic variants have been widely associated with obesity in children populations. The implication of such obesity pGRSs in the development of cardio-metabolic alterations during childhood as well as their utility for the clin...

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Bibliographic Details
Main Authors: Augusto Anguita-Ruiz, Esther M. González-Gil, Azahara I. Rupérez, Francisco Jesús Llorente-Cantarero, Belén Pastor-Villaescusa, Jesús Alcalá-Fdez, Luis A. Moreno, Ángel Gil, Mercedes Gil-Campos, Gloria Bueno, Rosaura Leis, Concepción M. Aguilera
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
obesity
childhood obesity
metabolic syndrome
genetics
genetic risk score
pharmacogenetics
Online Access:https://www.mdpi.com/2077-0383/9/6/1705

Internet

https://www.mdpi.com/2077-0383/9/6/1705

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