PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis.

In mammals, the liver plays a central role in maintaining carbohydrate and lipid homeostasis by acting both as a major source and a major sink of glucose and lipids. In particular, when dietary carbohydrates are in excess, the liver converts them to lipids via de novo lipogenesis. The molecular chec...

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Bibliographic Details
Main Authors: Yong-Sheng Cheng, Oksana Seibert, Nora Klöting, Arne Dietrich, Katrin Straßburger, Sonia Fernández-Veledo, Joan J Vendrell, Antonio Zorzano, Matthias Blüher, Stephan Herzig, Mauricio Berriel Diaz, Aurelio A Teleman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4595073?pdf=render