Evaluation of Low versus High Volume per Minute Displacement CO2 Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology

Evaluation of Low versus High Volume per Minute Displacement CO2 Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology

Current recommendations for the use of CO 2 as a euthanasia agent for rats require the use of gradual fill protocols (such as 10% to 30% volume displacement per minute) in order to render the animal insensible prior to exposure to levels of CO 2 that are associated with pain. However, exposing rats...

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Bibliographic Details
Main Authors: Debra L. Hickman, Stephanie D. Fitz, Cristian S. Bernabe, Izabela F. Caliman, Melissa M. Haulcomb, Lauren M. Federici, Anantha Shekhar, Philip L. Johnson
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Animals
Subjects:
CO2
hypercapnia
euthanasia
panic
anxiety
distress
Online Access:http://www.mdpi.com/2076-2615/6/8/45

Internet

http://www.mdpi.com/2076-2615/6/8/45

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